Novel mRNA-containing cytoplasmic granules in ALK-transformed cells

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Novel mRNA-containing cytoplasmic granules in ALK-transformed cells

In mammalian cells, nontranslating messenger RNAs (mRNAs) are concentrated in different cytoplasmic foci, such as processing bodies (PBs) and stress granules (SGs), where they are either degraded or stored. In the present study, we have thoroughly characterized cytoplasmic foci, hereafter called AGs for ALK granules that form in transformed cells expressing the constitutively active anaplastic ...

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ژورنال

عنوان ژورنال: Molecular Biology of the Cell

سال: 2011

ISSN: 1059-1524,1939-4586

DOI: 10.1091/mbc.e10-07-0569